In 2017, she developed the Lion Diet, a plant-free, ruminant-meat-based ketogenic elimination diet, to address lingering health issues and withdrawal symptoms. The diet has since helped tens of thousands of people manage autoimmune and psychiatric disorders, obesity, and severe food sensitivities. Guides, research, and resources live at liondiet.com. In 2026, the first clinical study is being run, delving into the efficacy of this and ketogenic diets on RA and IBD.
Since 2018, Mikhaila has managed her father Jordan B. Peterson's brand, overseeing PR, strategy, and social media. In 2020, she launched The Mikhaila Peterson Podcast, covering health, relationships, and psychology. Her recurring series, Opposing Views, features experts debating contentious topics on equal footing, designed to train the audience in critical thinking rather than deliver a verdict.